Искусственная почка, имитирующая гемодиализ, прошла лабораторные испытания

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Искусственная почка, имитирующая гемодиализ, прошла лабораторные испытания

Группа исследователей Калифорнийского университета в Сан-Франциско (UCSF) разработала и продемонстрировала прототип искусственной почки, которая поможет больным с почечной недостаточностью избавится от процедуры гемодиализа и сопутствующего ему приема лекарств.

Биоискусственная почка имплантируется и работает, как обычная почка, после чего больному не требуется принимать препараты, необходимые для искусственного угнетения иммунитета и для разжижения крови.

В состав имплантата входит гемофильтр, состоящий из кремниевых полупроводниковых мембран, очищающих кровь от шлаков и биореактора, в котором искусственные клетки почечных канальцев выполняют некоторые функции обмена веществ – регулируют объем воды, электролитный баланс и ряд других. Мембраны также предохраняют клетки от агрессии иммунной системы.

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В серии тестов каждая из частей была протестирована отдельно, а потом вместе на одном устройстве. Через искусственную почку проходят две основные артерии – по одной кровь поступает для очистки, а по другой – после фильтрации возвращается в организм.

В ходе экспериментов ученые доказали: биоискусственная почка работает, довольствуясь только кровяным давлением пациента, без необходимости использования специального медицинского оборудования.

Команда ученых планирует сфокусироваться на дальнейшем развитии технологиии, провести углубленные предклинические тесты, и в итоге выйти на клинические испытания.

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    References:

    Samual

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